Pre-filled syringe rotary filling machines are professional aseptic production equipment specially developed for pre-filled injectable syringes, widely applied in vaccine, cosmetic injection, insulin and ophthalmic liquid production workshops. Different from traditional bottle filling lines, pre-filled syringes have special tubular structures and rubber plungers, putting forward higher requirements on aseptic filling accuracy and pollution prevention; this rotary filling equipment adopts fully enclosed sterile design to meet the strict production standards of high-end injectable preparations.
The equipment adopts multi-station rotary indexing transmission structure, integrating syringe feeding, inner wall washing, drying sterilization, accurate liquid filling, rubber stopper pressing and output functions into one machine. Each station runs synchronously under servo motor control, with filling precision controlled within ±0.5%, effectively avoiding insufficient or over-filling of expensive injection raw materials. The liquid delivery pipeline is equipped with sterile filter membranes to ensure no microbial contamination during liquid transmission, and the whole filling cavity can be disinfected by online SIP steam sterilization without disassembly.
The fixture of the rotary turntable is customized for standard pre-filled syringes of different specifications (1ml, 3ml, 5ml, 10ml), and mold replacement can be finished within 15 minutes to switch different production batches. All contact liquid components are imported 316L stainless steel and medical-grade silicone, resistant to acid and alkali liquid medicines, and free of material precipitation that affects drug stability. The fully isolated operating cabin isolates the filling area from the external environment, maintaining Class 100 sterile environment inside the cabin during continuous production.
Matched with the ampoule vision inspection machine as the post-process quality control link, the full pre-filled syringe production line realizes automatic closed-loop production from empty syringe feeding to finished product defect detection. For biopharmaceutical factories with strict aseptic requirements, this rotary filling machine reduces human access to the sterile area, minimizes the risk of microbial contamination, and the automatic data recording function meets the traceability requirements of pharmaceutical industry production management, helping enterprises pass international industry compliance audits and enhance product market competitiveness.
